MonaVie (M)mūn™

New MonaVie (M)mūn™



Optimize your body’s natural defenses. MonaVie (M)mūn™ is a beneficial blend of 19 fruits and Wellmune®—clinically shown to promote proper immune function. Formulated with antioxidant rich MVao2, ™ a proprietary complex featuring the superfruits açai and maqui, this delicious juice helps protect your body year round. It’s your daily defense for a healthier life.

The official name of the product, pronounced “immune” is: (M)mūn

Recent News

MonaVie new product, to be officially announced during the January 4th global webcast, through social networking channels.

Monavie (M)mūn™ and the principal ingredient Wellmune® clinically proven to enhance innate immune cells.

Optimize your body’s natural defenses. MonaVie (M)mūn™ is a beneficial blend of 19 fruits and Wellmune®—clinically shown to promote proper immune function. Formulated with antioxidant rich MVao2, ™ a proprietary complex featuring the superfruits açai and maqui, this delicious juice helps protect your body year round. It’s your daily defense for a healthier life.

What is Wellmune?

Wellmune® is a natural ingredient that activates a large population of immune cells to defend the body against a wide range of foreign challenges. Derived from the cell walls of a proprietary strain of yeast, this unique gluco polysaccharride acts as a biological response modifier.

As the immune system evolved, it became very adept at killing yeast and fungi by recognizing certain molecules that commonly occur on the cell surface of these challenges. Wellmune is one such recognition molecule.

Wellmune binds to specific receptors (CR3) on neutrophils, the most abundant immune cell in the body, and activates or enhances its anti-microbial activity, including immune cell migration to the site of a challenge (chemotaxis) and increased killing of intruders (phagocytosis and oxidative burst).

The molecular structure of Wellmune, with its beta 1,3/1,6 branch points, is responsible for its unique biological activity. Wellmune® Enhanced Overall Wellness and Reduced Severity of Symptoms During Cold/Flu SeasonResearch Published in The Journal of Applied Research.






EAGAN, MN — August 3, 2009 — A new clinical study may offer a solution for people seeking to minimize the severity of health challenges during the cold/flu season.

According to research published recently in The Journal of Applied Research, a natural immune health ingredient called Wellmune® reduced the incidence of fever and eliminated the need for study subjects to miss work or school due to colds.

Wellmune® is clinically proven to enhance innate immune cells that are the body’s first line of defense. Derived from a proprietary strain of Baker’s yeast, Wellmune® white blood cells (neutrophils) to more quickly find and kill foreign challenges.

“The research indicates the potential of Wellmune® to naturally enhance the body’s immune system to improve overall health and wellness,” said Richard Mueller, chief executive officer of Biothera, the manufacturer of Wellmune.® “With all of the challenges we face today, strengthening your immune system with Wellmune® a great way to protect yourself.”

The randomized, double-blind, placebo-controlled study was conducted last year during the cold/flu season with 40 healthy subjects, aged 18-65. Subjects were treated daily with either Wellmune® or a placebo for 90 days. Cold/flu symptoms were evaluated by medical staff within 24 hours of onset.

While there were no significant differences in the incidence of symptomatic respiratory infections among the study groups, the duration and severity of symptoms were alleviated in subjects receiving Wellmune®.

In the study results, the Wellmune® group reported:

• No missed work or school due to colds, compared with 1.38 days of work/school missed for the placebo group. (p = 0.026)

• No incidence of fever, compared with 3.50 incidence in the placebo group. (p = 0.042)

• An increase in quality of life, including physical energy and emotional well-being, as measured by a clinically validated health survey questionnaire (SF-36v-2). (p = 0.042)

• No adverse events were detected and no safety concerns were present.

“Most of us cannot afford ‘down time,’” said Mueller. “Missing work or school, re-arranging schedules and just feeling lousy is inconvenient, to say the least. Now there is a simple, natural and safe way to support your family’s immune system.”

The study, entitled “Randomized Phase II Clinical Trials of Wellmune® for Immune Support During Cold and Flu Season,” was published in Vol. 9, No. 1 & 2 of The Journal of Applied Research. The study was conducted for Biothera by Miami Research Associates, Department of Nutrition and Endocrinology.

Research

Clinical research consistently demonstrates the ability of Wellmune® to naturally enhance human immune responses and provide protection from health challenges related to physical and lifestyle stress. Double-blind, placebo-controlled studies involving marathoners, firefighters and other individuals with stressful lifestyles found that Wellmune reduces incidence of upper respiratory tract infection symptoms and improves a sense of overall health.

These findings are not surprising based on the large body of published research demonstrating Wellmune® unique mechanism of action. Scientists understand how Wellmune works in the body at a cellular and intracellular level, making it perhaps the most researched functional ingredient in the world.

Equally important, research also documents what Wellmune® does not do: stimulate the immune system. Other immune health ingredients stress the immune system in ways that may be harmful over time. Wellmune® enhances natural immune function and is safe for daily consumption.

Patents

Biothera’s superior intellectual property and dominant patent position provides customers with confidence in the safety, efficacy and long-term availability of the company's products. Biothera has more than 40 U.S. patents and patents pending, with additional filings in more than 20 countries that protect:

Matter of composition
Manufacturing processes
Applications

Biothera has successfully defended its patents in U.S. courts against infringement. The company intends to continue to vigorously protect its intellectual property rights.

About Wellmune®
Wellmune® is a functional food, beverage and dietary supplement ingredient available worldwide through Biothera and its distributors. This natural compound (gluco polysaccharide) is isolated from the cell walls of a proprietary strain of yeast. Wellmune® is Generally Regarded As Safe (GRAS) under U.S. Food and Drug Administration regulations. It also is Kosher, HALAL, non-allergenic and GMO-free. Numerous peer-reviewed studies support the safety and efficacy of Wellmune® which is the culmination of years of research and a technology investment of more than $250 million.

New MonaVie (M)mūn™ Fruit Descriptions

1. Juçara
Juçara is also an açai palm tree, which is native to South America. A drink made with this form of açai is widely consumed by the inhabitants of the northern region of Brazil. The juçara açai palm produces dark purple fruit that looks similar to a grape or blueberry. This fruit is rich in polyphenol antioxidants. According to laboratory testing, the juçara açai fruit has a strong ORAC value when compared to other fruits and vegetables.

2. Maqui berry
(pronounced: mä-key) Maqui is a plant that grows in Chile and western Argentina. The deep purple maqui berry has been used traditionally for a variety of benefits including support for immune health and vitality. The maqui berry contains powerful antioxidants including polyphenols and anthocyanins, which help protect against the damaging effects free radicals can have on our cells and support healthier aging.

3. Baobab
The baobab tree is native to the tropical lands of Africa. The elongated oval shaped baobab fruit (like a potato) has a hard shell covered with soft yellowish-gray fur. The literature is abundant for its traditional use as a food. The most edible and frequently consumed part of this popular African fruit is the inner pulp. The pulp is commonly eaten raw or mixed with milk or water to make a drink. Vitamin C is one of the most prominent nutrients found in the baobab fruit.

4. Black currant
Black currant is native to Europe and northern Asia. A variety of black currant is also found in North America. It is cultivated for its fruit, which is used in jelly, pudding, tarts and in making spirits. Black currant fruit is a source of vitamin C, an essential vitamin with antioxidant properties. It has been studied for its anthocyanin content; an antioxidant that gives this berry its distinctive color.

5. Blood orange
In Sicily, the "blood" orange gained its nickname because of its ruby flesh that contains the red pigment, anthocyanin, a strong antioxidant. Sicilian Red oranges deliver more than instant gratification in the form of flavor and sweetness. They also contain nutritional and health supporting properties. Blood oranges have been used in home remedies for centuries. They are known for their vitamin C content.

6. Elderberry
Elderberries are small, dark berries that grow in clusters on elder bushes (also called elderberry trees). There are many different varieties of elderberry trees. Elderberry bushes are a hardy plant growing native in many climates in Europe and North America. The berries are said to have many nutritional benefits. Elderberries contain vitamin C, which is commonly used to support the immune system. Elderberries also have anthocyanins, antioxidants which are responsible for giving many red and purple fruits their color.

7. Strawberry
It is commonly believed that strawberries were cultivated back in Ancient Rome. In the 13th century, strawberries were used in France as a medicinal herb. The most common strawberry cultivated today, a hybrid variety known as the garden strawberry from Europe, is noted for its intense flavor and large size. The bright red aggregate fruit contains antioxidants and other beneficial phytonutrients.

8. Lingonberry
Lingonberry is a creeping, evergreen, sub-shrub native to North America, Europe, and Asia. It is widely distributed in arctic, alpine, and northern temperate forest regions. The fruit is bright to dark red, strong flavored, and tart. Lingonberries contain beneficial nutrients such as vitamins and antioxidant polyphenol compounds.

9. Sea Buckthorn
Sea Buckthorn is a hardy deciduous shrub native to Asia and Northwestern Europe. Other countries who are cultivating this shrub include Canada, Germany, Japan, and northern European countries. It has been produced for centuries in Europe and Asia as a foodstuff and traditional remedy. The shrub produces yellow-orange to red berries that contain vitamins and other nutrients such as vitamins A, C, and E, and other nutritional compounds.